Hogge Research Group
Principal Investigator:
W. Allen Hogge, MD
Dr. Hogge’s Research Lab focuses on two areas of pregnancy complications: The genetic etiology of recurrent pregnancy loss, for which the lab has collaborative relationships with a number of individuals in this area, and; Non-invasive diagnosis of genetic conditions. The lab’s active screening program is used to assess alternative methods of more focus screening and/or diagnosis of fetal genetic conditions. The lab works very closely with the laboratory of Dr. David Peters at Magee-Womens Research Institute.
Lab Members
Heather A. Bakos (Huber), BS
Lab Alumni
Mark C. Lanasa, MD, PhD
Assistant Professor of Medicine
Duke University
Tracy L. Prosen, MD
Assistant Professor
University of Minnesota
Selected Publications
- Founds SA, Conley YP, Lyons-Weiler J, Jeyabalan A, Hogge WA, & Conrad, KP. Altered global gene expression in first trimester placentas of women destined to develop preeclampsia. Placenta, 30:15-24, 2009.
- Chu T, Bunce K, Hogge WA, & Peters DG. Statistical model for whole genome sequencing and its application to minimally invasive diagnosis of fetal genetic disease. Bioinformatics, 25:1244-50, May 2009.
- Chu T, Burke B, Bunce K, Handley D, Surti U, Hogge WA, & Peters DG. A Microarray-based approach for the identification of epigenetic biomarkers for the minimally-invasive diagnosis of fetal disease. Prenat Diag, 29:1020-30, 2009.
- Founds SA, Terhorst LA, Conrad KP, Hogge WA, Jeyabalan A, & Conley YP. Gene expression of eight candidates in first trimester preeclampsia placenta. Biolog Res for Nursing, Nov. 2009 (in press).
- Berger DS, Hogge WA, Barmada MM, & Ferrell RE. Comprehensive analysis of HLA-G: Implications for recurrent spontaneous abortion. Accepted for publication in Reprod Sci, Dec. 2009.